---
title: "CVE-2026-100846: MONAI - Insecure Deserialization"
description: "MONAI < 1.5.2 contains an insecure deserialization vulnerability caused by untrusted data passed to pickle.loads in algo_from_pickle function, letting attackers execute arbitrary code remotely, exploit requires attacker-supplied pickle file."
url: https://panop.io/threat-heartbeat/CVE-2026-100846/
---

# CVE-2026-100846 MONAI - Insecure Deserialization

MONAI < 1.5.2 contains an insecure deserialization vulnerability caused by untrusted data passed to pickle.loads in algo\_from\_pickle function, letting attackers execute arbitrary code remotely, exploit requires attacker-supplied pickle file.

CVSS base score 7.6 /10

High

CISA KEV

Not listed

Public exploit

Proof of concept available

Authentication

Required

EPSS

0.29% chance of exploitation in 30 days

[View the NVD record ↗](https://nvd.nist.gov/vuln/detail/CVE-2026-100846)

## Details

Type

Insecure Deserialization

Impact

Remote Code Execution

CVSS vector

CVSS:3.1/AV:N/AC:H/PR:H/UI:R/S:C/C:H/I:H/A:H

Published

27 September 2026

Updated

15 October 2026

Weakness

[CWE-502](https://cwe.mitre.org/data/definitions/502.html)

## Vendor fix

Upgrade to version 1.5.2 or later.

Patching closes this CVE. It does not tell you which of your systems run the affected version, or what else is exposed alongside them.

## References

- [https://nvd.nist.gov/vuln/detail/CVE-2026-100846](https://nvd.nist.gov/vuln/detail/CVE-2026-100846)
- [https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4](https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4)
- [https://www.vulncheck.com/advisories/monai-before-1.5.2-remote-code-execution-via-pickle-deserialization](https://www.vulncheck.com/advisories/monai-before-1.5.2-remote-code-execution-via-pickle-deserialization)

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## What this record can't tell you

- Whether you run the affected software, and where
- Whether an attacker can actually reach and exploit it
- The misconfigurations that never get a CVE number
- What it would cost the business, ranked into what to fix first

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